Zuprevo 18% is indicated for the treatment of bovine respiratory disease (BRD) associated withMannheimia haemolytica, Pasteurella multocida, andHistophilus somniin beef and non-lactating dairy cattle, and for the control of respiratory disease in beef and non-lactating dairy cattle at high risk of developing BRD associated withMannheimia haemolytica, Pasteurella multocida, andHistophilus somni.