C.E.T.® Enzymatic Oral Hygiene Chews for Dogs, featuring the exclusive Dual-Enzyme System, are made from select beef hide. It combines a natural antiseptic, plus its abrasive texture that works with the dog's chewing action to loosen tartar and provide clinically-proven plaque control. C.E.T. Enzymatic Oral Hygiene Chews for Dogs helps clean teeth and freshen breath even when brushing isn't possible. Dogs will love its appealing poultry flavor. May be given daily.